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At Charak Hospital, our experienced transplant surgeons and nephrologists perform kidney transplants from living and deceased donors with excellent graft survival rates. Comprehensive evaluation, expert surgery, and lifelong immunosuppression support ensure superior outcomes and quality of life restoration.
Patients with end-stage renal disease eligible for transplantation.
Patients with ESRD (GFR <15 mL/min/1.73m²) on dialysis for >6 months. Stable medical condition, cardiac fitness, psychological stability. Age alone not a contraindication;
elderly with good health may transplant. No active infection or malignancy.
Comprehensive assessment: blood typing, HLA testing, cross-matching with donor. Cardiac workup (ECG, echocardiogram, stress test if indicated). Infectious disease screening (HIV, Hep B/C, TB). Cancer screening colonoscopy/mammography. Psychological assessment and social support evaluation.
Active malignancy (>2-5 years from remission needed), active infection or sepsis, severe cardiac disease, severe immunosuppression risk, non-compliance concerns. Evaluate on case-by-case basis.
Two donor sources offer different advantages.
Kidney from living relative, friend, or altruistic donor. Shorter surgical time, planned procedure, minimal ischemia time. Superior 1-year (95%) and long-term graft survival (15+ years). Living donor evaluated thoroughly—kidney function preserved, no surgical complications, informed consent.
Kidney from brain-dead or cardiac-dead donor. Variable waitlist time (1-5 years). Longer ischemia time affects short-term function. Good outcomes but slightly lower graft survival (90% 1-year, 10-12 years average). Deceased donors expand opportunity for transplant access.
How kidney transplant surgery is performed.
General anesthesia. Patient position supine or slight oblique. Surgical site (usually right iliac fossa) prepped and draped. Recipient's native kidneys usually left in place unless specific complications (chronic infection, malignancy). Vascular access site for monitoring.
Incision over iliac fossa. Retroperitoneal dissection exposing iliac vessels. Vascular anastomosis: donor kidney artery to recipient iliac artery; donor vein to recipient iliac vein (end-to-side). Ureteroneocystostomy: donor ureter sutured to recipient bladder trigone (creates antireflux valve). Careful hemostasis. Closure in layers. Surgery typically 2-3 hours.
Induction therapy: anti-thymocyte globulin (ATG) or basiliximab to deplete/block T cells. Corticosteroids given. Maintenance: tacrolimus/cyclosporine, mycophenolate, prednisone started perioperatively.
For living donors: minimally invasive laparoscopic approach. 3 small incisions, decreased pain, faster recovery. Graft outcomes equivalent to open surgery. Preferred when feasible.
Timeline and expectations after kidney transplant.
Early and late complications occur in 20-30% of transplants.
Delayed graft function (DGF): impaired initial function requiring dialysis—common with deceased donor, extended ischemia. Usually reverses within days-weeks. Vascular: thrombosis, stenosis requiring intervention. Urine leak from ureteroneocystostomy requiring stent/re-operation.
Chronic rejection: insidious graft function decline. Infection: CMV, other viral/bacterial. Malignancy: lymphoproliferative disorder (EBV), skin cancer. Recurrent disease (glomerulonephritis, diabetes). Cardiovascular disease (hypertension, atherosclerosis).
Lifelong medications required. Balance: prevent rejection but minimize infection/malignancy risk. Tacrolimus/cyclosporine (calcineurin inhibitors), mycophenolate (antimetabolite), prednisone (corticosteroid). Regular blood level monitoring, dose adjustments based on drug levels and kidney function.
Fellowship-trained transplant surgeons and nephrologists with 100+ transplants/year experience.
95% 1-year graft survival, 85%+ 5-year graft survival. Superior outcomes to national average.
Pre-transplant evaluation, surgery, immunosuppression management, lifelong follow-up, complications management.
Transplant surgery ₹5-7 lakh. Donor nephrectomy ₹2-3 lakh. Ayushman Bharat & insurance covered.
Laparoscopic donor nephrectomy, modern immunosuppression, state-of-the-art monitoring.
All procedures meet highest safety and transplant standards.
Long-term management ensures graft longevity.
📍 Charak Hospital & Research Centre, Hardoi Road, near Safaid Masjid, Dubagga, Lucknow – 226003.
Serving patients from Lucknow, Hardoi, Sitapur, Unnao, Barabanki and across Uttar Pradesh.
Fellowship-trained urologists specializing in living and deceased donor kidney transplantation.
Senior Urologist & Kidney Transplant Specialist
Fellowship-trained in kidney transplantation. Expert in both living and deceased donor transplants with excellent long-term graft outcomes.
View ProfileUrologist & Kidney Transplant Specialist (17+ years)
Expert in kidney transplantation with 17+ years experience. Specializes in complex cases and provides comprehensive post-transplant care.
View ProfileOur Institute of Urology and Kidney Transplant is recognized for excellence in transplant outcomes and patient care.
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